As a result of more balanced blade aspect ratios of modern blade-integrated disks (blisks), interactions between disk-dominated and blade-dominated modes are becoming more and more important, especially if blade mistuning is considered. The specific vibration behavior in these transition regions is characterized by a mix of both fundamental mode types into “coupled” modes. In this paper, numerical and experimental investigations based on a front high-pressure compressor (HPC) blisk stage were carried out in order to determine the effect of blade mistuning on those regions in detail. At this, effects like mode localization and amplitude magnification are found to be weakened in an integer frequency-veering zone. Contrary to this, blisks are very sensitive to mistuning in regions of pure blade-dominated mode families with high modal density.