In much of the public literature on pin-fin heat transfer, the Nusselt number is presented as a function of Reynolds number using a power-law correlation. Power-law correlations typically have an accuracy of 20% while the experimental uncertainty of such measurements is typically between 5% and 10%. Additionally, the use of power-law correlations may require many sets of empirical constants to fully characterize heat transfer for different geometrical arrangements. In the present work, artificial neural networks were used to predict heat transfer as a function of streamwise spacing, spanwise spacing, pin-fin height, Reynolds number, and row position. When predicting experimental heat transfer data, the neural network was able to predict 73% of array-averaged heat transfer data to within 10% accuracy while published power-law correlations predicted 48% of the data to within 10% accuracy. Similarly, the neural network predicted 81% of row-averaged data to within 10% accuracy while 52% of the data was predicted to within 10% accuracy using power-law correlations. The present work shows that first-order heat transfer predictions may be simplified by using a single neural network model rather than combining or interpolating between power-law correlations. Furthermore, the neural network may be expanded to include additional pin-fin features of interest such as fillets, duct rotation, pin shape, pin inclination angle, and more making neural networks expandable and adaptable models for predicting pin-fin heat transfer.