A new high-speed linear cascade has been developed for low-pressure turbine (LPT) studies at The Ohio State University. A compressible LPT profile is tested in the facility and its baseline performance at different operating conditions is assessed by means of isentropic Mach number distribution and wake total pressure losses. Active flow control is implemented through a spanwise row of vortex-generator jets (VGJs) located at 60% chord on the suction surface. The purpose of the study is to document the effectiveness of VGJ flow control in high-speed compressible flow. The effect on shock-induced separation is assessed by Mach number distribution, wake loss surveys and shadowgraph. Pressure sensitive paint (PSP) is applied to understand the three dimensional flow and shock pattern developing from the interaction of the skewed jets and the main flow. Data show that with increasing blowing ratio, the losses are first decreased due to separation reduction, but losses connected to compressibility effects become stronger due to increased passage shock strength and jet orifice choking; therefore, the optimum blowing ratio is a tradeoff between these counteracting effects. The effect of added surface roughness on the uncontrolled flow and on flow control behavior is also investigated. At lower Mach number, turbulent separation develops on the rough surface and a different flow control performance is observed. Steady VGJs appear to have control authority even on a turbulent separation but higher blowing ratios are required compared to incompressible flow experiments reported elsewhere. Overall, the results show a high sensitivity of steady VGJs control performance and optimum blowing ratio to compressibility and surface roughness.