New geometric mistuning modeling approaches for integrally bladed rotors (IBRs) are developed for incorporating geometric perturbations to a fundamental disk–blade sector, particularly the disk–blade boundary or connection. Reduced-order models (ROMs) are developed from a Craig–Bampton component mode synthesis (C–B CMS) framework that is further reduced by a truncated set of interface modes that are obtained from an Eigen-analysis of the C–B CMS constraint degrees of freedom (DOFs). An investigation into using a set of tuned interface modes and tuned constraint modes for model reduction is then performed, which offers significant computational savings for subsequent analyses. Two configurations of disk–blade connection mistuning are investigated: as-measured principal component (PC) deviations and random perturbations to the interblade spacing. Furthermore, the perturbation sizes are amplified to investigate the significance of incorporating mistuned disk–blade connections during solid model generation from optically scanned geometries. Free and forced response results are obtained for each ROM and each disk–blade connection type and compared to full finite element model (FEM) solutions. It is shown that the developed methods provide accurate results with a reduction in solution time compared to the full FEM. In addition, results indicate that the inclusion of a mistuned disk–blade connection deviations are small or conditions where large perturbations are localized to a small areas of the disk–blade connection.