This paper covers a comprehensive forced response analysis conducted on a multistage compressor and compared with the largest forced response experimental data set ever obtained in the field. The steady-state aerodynamic performance and stator wake predictions compare well with the experimental data, although losses are underestimated. Coupled and uncoupled unsteady simulations are conducted on the stator–rotor configuration. It is shown that the use of a decoupled method for forced response cannot yield accurate results for cases with strong inter-row interactions. The individual and combined contributions of the upstream and downstream stators are also assessed. The downstream stator is found to have a tremendous impact on the forced response predictions due to the constructive interactions of the two stator rows. Finally, predicted mistuned blade amplitudes are compared to mistuned experimental data. The average amplitudes match the experiments very well, while the maximum response amplitude is underestimated.