The Convection-Enhanced Thermo-Therapy Catheter System (CETCS) was developed by our group at The University of Texas at Austin for the treatment of glioblastoma. This arborizing catheter is remotely operated and provides the ability to position and infuse in regions of the tumor and tumor margins to increase the dispersal volume coverage capability. The next step in developing this device is the further characterization of the materials being used in this design.
Device characterization included evaluating the behavior of the microneedles under compression while they were in contact with several types of durometers (50A, 80A, 90A, and 95A). This test method was used to determine if the microneedles would experience breakage at the tip or along the microneedle.
After the compression-durometer testing, it was determined the tips of the microneedles were more likely to puncture the durometer prior to experiencing any breakage. The device’s microneedles are not expected to come into contact with materials that have a higher durometer rating of 50A and will be acceptable in the current CETCS design meant for the treatment of glioblastomas.