A simple and explicit representation for the anisotropic elastic constants of human cancellous bone was determined using a new method of analysis on a data base consisting of 141 human cancellous bone specimens. The method of analysis shows that human cancellous bone has orthotropic elastic symmetry at the 95% confidence level and it also provides expressions for all the orthotropic elastic constants as functions of the volume fraction of solid only; no stereological measures of trabecular architecture are involved. This result should be employed to improve the in vivo evaluation of cancellous bone stiffness and strength from a standard clinical test.

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