Atherosclerotic plaque rupture is the main cause of myocardial infarction, coronary thrombosis and stroke. Current clinical observations suggest that an advanced plaque features a thin, collagen-rich fibrous cap infiltrated by macrophages, overlying a large lipid core rich in lipid-laden macrophages. However, due to relatively poor understanding of mechanisms associated with plaque rupture, there is no quantitative standard for plaque stability estimation.
- Bioengineering Division
Development of a Quantitative Mechanical Test of Atherosclerotic Plaque Stability
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Wang, Y, Ning, J, Sutton, MA, & Lessner, SM. "Development of a Quantitative Mechanical Test of Atherosclerotic Plaque Stability." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 35-36. ASME. https://doi.org/10.1115/SBC2010-19489
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