Micro features were created in thin film NiTi using a novel lift-off process to create an endovascular biomedical device. This manuscript describes fabrication problems with wet etching and introduces an effective way, named “Lift-off” process to solve undercut and nonuniform pattern issues. Two lift-off processes (i.e., lift-off I and II) are discussed. Lift-off I process has fracture issues and the film peels off the substrate due to high aspect ratio post structures. Lift-off II process use the film on the top of the Si substrate to fabricate various shape patterns (i.e., ellipse, diamond, circle, square, etc.) in the range of 5∼60μm. The lift-off II process shows smooth and well aligned micro patterns in thin film NiTi. In-vivo tests in swine were performed to evaluate the endothelial tissue growth through fabricated micro patterns. Angiography and SEM images show patency of the artery and a uniform endothelial layer covering the device without thromobosis.
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Fabrication Processes for Creating Micro Features in Thin Film NiTi Endovascular Grafts
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Chun, Y, Levi, DS, Mohanchandra, KP, & Carman, GP. "Fabrication Processes for Creating Micro Features in Thin Film NiTi Endovascular Grafts." Proceedings of the ASME 2009 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. Volume 2: Multifunctional Materials; Enabling Technologies and Integrated System Design; Structural Health Monitoring/NDE; Bio-Inspired Smart Materials and Structures. Oxnard, California, USA. September 21–23, 2009. pp. 603-609. ASME. https://doi.org/10.1115/SMASIS2009-1249
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