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Journal Articles

Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery

Timoleon Kipouros, Ibrahim Chamseddine, Michael Kokkolaras

J Biomech Eng. April 2022, 144(4): 044501.

Paper No: BIO-21-1174

DOI: https://doi.org/10.1115/1.4052578

Published Online: November 5, 2021

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Topics: Design, Drug delivery systems, Nanoparticles, Optimization, Tumors, Modeling, Drugs

Journal Articles

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

Adithya Gurumurthy, Clement Kleinstreuer

J Biomech Eng. November 2021, 143(11): 111001.

Paper No: BIO-21-1035

DOI: https://doi.org/10.1115/1.4051217

Published Online: July 14, 2021

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Topics: Aerosols, Drugs, Flow (Dynamics), Nanoparticles, Particulate matter, Lung, Diffusion (Physics), Fluids, Drug delivery systems

Journal Articles

Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia

Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Randrianalisoa, Zhenpeng Qin

J Biomech Eng. March 2021, 143(3): 031004.

Paper No: BIO-20-1113

DOI: https://doi.org/10.1115/1.4049017

Published Online: December 10, 2020

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Topics: Heating, Nanoparticles, Proteins, Temperature, Materials properties, Lasers, Shapes

Includes: Supplementary data

Journal Articles

A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue

Ibrahim M. Chamseddine, Michael Kokkolaras

J Biomech Eng. December 2020, 142(12): 124501.

Paper No: BIO-19-1462

DOI: https://doi.org/10.1115/1.4047657

Published Online: September 8, 2020

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Topics: Drugs, Nanoparticles, Tumors, Biological tissues, Optimization

Journal Articles

Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery

Ibrahim M. Chamseddine, Michael Kokkolaras

J Biomech Eng. April 2018, 140(4): 041002.

Paper No: BIO-17-1243

DOI: https://doi.org/10.1115/1.4038202

Published Online: January 19, 2018

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Topics: Drugs, Nanoparticles, Optimization, Tumors, Design, Vessels, Shapes

Journal Articles

Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect

David P. Eisenberg, John C. Bischof, Yoed Rabin

J Biomech Eng. January 2016, 138(1): 011010.

Paper No: BIO-15-1343

DOI: https://doi.org/10.1115/1.4032053

Published Online: December 8, 2015

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Topics: Cryonics, Heating, Nanoparticles, Stress, Temperature, Thermomechanics, Vitrification, Cooling, Heat transfer, Crystallization

Journal Articles

Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates

Matthew R. DeWitt, Allison M. Pekkanen, John Robertson, Christopher G. Rylander, Marissa Nichole Rylander

J Biomech Eng. February 2014, 136(2): 021003.

Paper No: BIO-13-1471

DOI: https://doi.org/10.1115/1.4026318

Published Online: February 5, 2014

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Topics: Carbon, Drugs, Heat, Nanoparticles, Tumors, Temperature, Heating, Particulate matter, Patient treatment, Diffusion (Physics)

Journal Articles

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part I: Whole-Lung Aerosol Dynamics

Arun V. Kolanjiyil, Clement Kleinstreuer

J Biomech Eng. December 2013, 135(12): 121003.

Paper No: BIO-13-1174

DOI: https://doi.org/10.1115/1.4025332

Published Online: October 9, 2013

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Topics: Dynamics (Mechanics), Flow (Dynamics), Lung, Nanoparticles, Particulate matter, Fluids

Journal Articles

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part II: Multi-Compartmental Modeling

Arun V. Kolanjiyil, Clement Kleinstreuer

J Biomech Eng. December 2013, 135(12): 121004.

Paper No: BIO-13-1175

DOI: https://doi.org/10.1115/1.4025333

Published Online: October 9, 2013

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Topics: Lung, Nanoparticles, Particulate matter, Modeling, Clearances (Engineering), Mass transfer

Journal Articles

Hydrodynamic Modeling of Targeted Magnetic-Particle Delivery in a Blood Vessel

Huei Chu Weng

J Biomech Eng. March 2013, 135(3): 034504.

Paper No: BIO-12-1411

DOI: https://doi.org/10.1115/1.4023137

Published Online: February 11, 2013

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Topics: Biomedicine, Blood vessels, Flow (Dynamics), Magnetic fields, Magnetic fluids, Magnetic particles, Modeling, Nanoparticles, Particulate matter, Drag (Fluid dynamics)

Journal Articles

Theoretical Study on Temperature Dependence of Cellular Uptake of QDs Nanoparticles

Aili Zhang, Yingxue Guan, Lisa X. Xu

J Biomech Eng. December 2011, 133(12): 124502.

DOI: https://doi.org/10.1115/1.4005481

Published Online: December 21, 2011

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Topics: Fluorescence, Nanoparticles, Temperature, Cell membranes

Journal Articles

Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds

N. K. Bawolin, M. G. Li, X. B. Chen, W. J. Zhang

J Biomech Eng. November 2010, 132(11): 111001.

DOI: https://doi.org/10.1115/1.4002551

Published Online: October 12, 2010

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Topics: Finite element model, Mechanical properties, Modeling, Molecular weight, Tissue scaffolds, Young's modulus, Nanoparticles, Elasticity, Finite element analysis, Tissue engineering

Journal Articles

Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics

Todd O. Pangburn, Matthew A. Petersen, Brett Waybrant, Maroof M. Adil, Efrosini Kokkoli

J Biomech Eng. July 2009, 131(7): 074005.

DOI: https://doi.org/10.1115/1.3160763

Published Online: July 31, 2009

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Topics: Cancer, DNA, Drug delivery systems, Drugs, Nanoparticles, Proteins, Tumors, Vehicles, Patient treatment

Journal Articles

Nanoparticles for Thermal Cancer Therapy

Emily S. Day, Jennifer G. Morton, Jennifer L. West

J Biomech Eng. July 2009, 131(7): 074001.

DOI: https://doi.org/10.1115/1.3156800

Published Online: July 16, 2009

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Topics: Cancer, Heating, Nanoparticles, Patient treatment, Tumors, Radiofrequency ablation, Biological tissues, Temperature

Journal Articles

Numerical Simulation of Au Nanoparticles Effect on the PCR Process

Chao Chen, Aili Zhang, Xiaodong Zhang, Jun Hu, Lisa X. Xu

J Biomech Eng. July 2009, 131(7): 074512.

DOI: https://doi.org/10.1115/1.3147746

Published Online: June 12, 2009

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Topics: Nanoparticles, DNA

Journal Articles

An Adjustable Triple-Bifurcation Unit Model for Air-Particle Flow Simulations in Human Tracheobronchial Airways

C. Kleinstreuer, Z. Zhang

J Biomech Eng. February 2009, 131(2): 021007.

DOI: https://doi.org/10.1115/1.3005339

Published Online: December 10, 2008

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Topics: Bifurcation, Nanoparticles, Particulate matter, Turbulence, Flow (Dynamics), Lung, Simulation

Journal Articles

Effects of Oral Airway Geometry Characteristics on the Diffusional Deposition of Inhaled Nanoparticles

Jinxiang Xi, P. Worth Longest

J Biomech Eng. February 2008, 130(1): 011008.

DOI: https://doi.org/10.1115/1.2838039

Published Online: February 7, 2008

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Topics: Aerosols, Flow (Dynamics), Nanoparticles, Particulate matter, Turbulence, Geometry

Journal Articles

Laminar Airflow and Nanoparticle or Vapor Deposition in a Human Nasal Cavity Model

H. Shi, C. Kleinstreuer, Z. Zhang

J Biomech Eng. October 2006, 128(5): 697–706.

DOI: https://doi.org/10.1115/1.2244574

Published Online: March 6, 2006

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Topics: Air flow, Cavities, Flow (Dynamics), Nanoparticles, Particulate matter, Transients (Dynamics)

Journal citation

NARROW

Supplemental Material

Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia

A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue

Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery

Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect

Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part I: Whole-Lung Aerosol Dynamics

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part II: Multi-Compartmental Modeling

Hydrodynamic Modeling of Targeted Magnetic-Particle Delivery in a Blood Vessel

Theoretical Study on Temperature Dependence of Cellular Uptake of QDs Nanoparticles

Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds

Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics

Nanoparticles for Thermal Cancer Therapy

Numerical Simulation of Au Nanoparticles Effect on the PCR Process

An Adjustable Triple-Bifurcation Unit Model for Air-Particle Flow Simulations in Human Tracheobronchial Airways

Effects of Oral Airway Geometry Characteristics on the Diffusional Deposition of Inhaled Nanoparticles

Laminar Airflow and Nanoparticle or Vapor Deposition in a Human Nasal Cavity Model

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