... states. biological tissues biomechanics deformation tissue engineering mechanobiology fibrin matrix remodeling cyclic stretch mechanical strain tissue engineering Cells within skin and other connective tissues are continuously subjected to a range of mechanical forces from...

...Zhensong Wei; Vikram S. Deshpande; Robert M. McMeeking; Anthony G. Evans Numerical simulations that incorporate a biochemomechanical model for the contractility of the cytoskeleton have been used to rationalize the following observations. Uniaxial cyclic stretching of cells causes stress fibers...

... importance of each stimulus in producing the normal in vivo state is not clear. Using cultured human aortic endothelial cells, this study first determined equipotent levels of cyclic stretch, steady FSS, and oscillatory FSS with respect to the time course of cell orientation. We then tested whether...