The poly(L-lactic acid) (PLLA) has potential medical usage such as drug delivery since it can degrade into bioabsorbable products in physiological environments, while the degradation is affected by its crystallites. In this paper, the effects of film formation method and annealing on the crystallites formed in PLLA films are investigated. The films are made through solvent casting and spin coating, and subsequent annealing is conducted. The resulting morphology, molecular order, conformation, and intermolecular interaction are examined using optical microscopy, wide-angle X-ray diffraction, and Fourier transform infrared spectroscopy. It is observed that solvent casting produces category 1 spherulites while annealing the spin coated films leads to spherulites of category 2. The crystal structure of the two kinds of films also shows distinct features. The results enable better understanding of the crystallites in PLLA, which is essential for its medical application.
Skip Nav Destination
Article navigation
April 2014
Research-Article
Effect of Film Formation Method and Annealing on Morphology and Crystal Structure of Poly(L-Lactic Acid) Films
Shan-Ting Hsu,
Shan-Ting Hsu
Department of Mechanical Engineering,
e-mail: sh@caa.columbia.edu
Columbia University
,New York, NY 10027
e-mail: sh@caa.columbia.edu
Search for other works by this author on:
Y. Lawrence Yao
Y. Lawrence Yao
Department of Mechanical Engineering,
e-mail: yly1@columbia.edu
Columbia University
,New York, NY 10027
e-mail: yly1@columbia.edu
Search for other works by this author on:
Shan-Ting Hsu
Department of Mechanical Engineering,
e-mail: sh@caa.columbia.edu
Columbia University
,New York, NY 10027
e-mail: sh@caa.columbia.edu
Y. Lawrence Yao
Department of Mechanical Engineering,
e-mail: yly1@columbia.edu
Columbia University
,New York, NY 10027
e-mail: yly1@columbia.edu
Manuscript received February 7, 2011; final manuscript received October 25, 2013; published online January 10, 2014. Assoc. Editor: Yong Huang.
J. Manuf. Sci. Eng. Apr 2014, 136(2): 021006 (9 pages)
Published Online: January 10, 2014
Article history
Received:
February 7, 2011
Revision Received:
October 25, 2013
Citation
Hsu, S., and Lawrence Yao, Y. (January 10, 2014). "Effect of Film Formation Method and Annealing on Morphology and Crystal Structure of Poly(L-Lactic Acid) Films." ASME. J. Manuf. Sci. Eng. April 2014; 136(2): 021006. https://doi.org/10.1115/1.4025909
Download citation file:
Get Email Alerts
In-Situ Monitoring and Its Correlation to Mechanical Properties in Additively Manufactured 718 Ni Alloy
J. Manuf. Sci. Eng (March 2025)
NoodlePrint: Cooperative Multi-Robot Additive Manufacturing With Helically Interlocked Tiles
J. Manuf. Sci. Eng (June 2025)
Related Articles
Effects of Particle-Induced Crystallization on Tribological Behavior of Polymer Nanocomposites
J. Tribol (April,2011)
Critical Plane Fatigue Modeling and Characterization of Single Crystal Nickel Superalloys
J. Eng. Gas Turbines Power (April,2004)
A Thermodynamic Framework for Describing Solidification of Polymer Melts
J. Eng. Mater. Technol (January,2006)
Development of Nanoporous Ultrathin Membranes For Implantable Drug Delivery
J. Med. Devices (June,2008)
Related Proceedings Papers
Related Chapters
Crystal Orientation Optimization of Nickel-Based Single Crystal Turbine Blade
International Conference on Optimization Design (ICOD 2010)
Chitosan-Based Drug Delivery Systems
Chitosan and Its Derivatives as Promising Drug Delivery Carriers
The Direct Contribution of Spin-Down Compression for Rotochemical Deviations in Stars Containing Mixed- Phase Matter
International Conference on Advanced Computer Theory and Engineering, 4th (ICACTE 2011)