Discrete tip injection is an effective method to enhance stability of compressors. This study compares the effects of injection parameters on compressor performance and underlying mechanisms in two different compressors. The transonic compressor is studied using unsteady simulations, and the subsonic compressor is mainly investigated with experiments. Results show that tip injection improves stable operating range by 35.6% and 77.9% for the transonic compressor and subsonic compressor, respectively, without decreasing compressor efficiency. The effects of circumferential coverage percentage and injector throat height on compressor stability are similar in the two compressors when the injection velocity is double the velocity of the main flow. The optimal injector throat height which is normalized by the tip clearance size is the same for the two compressors, and the best circumferential coverage percentage for the subsonic compressor is lower than that in the transonic compressor. For the two compressors, the adaption of the main flow to the discrete tip injection is unsteady, and the hysteresis effect that the recovery of tip blockage lags behind the recovery of tip leakage vortex accounts for the improved stability using partial coverage of injection. The injection efficiency, which is defined to quantify the improved quality of the flow field in the injection domain, is proven to determine the stall limits by studying the effects of different injection parameters. The guidelines built in the subsonic compressor can be used in the transonic compressor to design tip injection, but the optimal values of some injection parameters should be reconfirmed.